SMi is revolutionising the world of molecular science by coupling deep learning with super-resolution imaging to provide unprecedented quantification of single molecules.

SMi’s flexible, high-throughput platform delivers fast, accurate and reliable results that reduce project complexity and enable scientists and clinicians to make better informed decisions. With SMi’s platform, discoveries and diagnoses are faster, more efficient and cost-effective.

The use of microscopy to observe biological processes has undergone huge advances in the last decade, an achievement recognised with Nobel Prizes for Chemistry in 2014 and 2017. A paralleled increase in commercial investment has coincided with huge technological advances that improve the speed and quality of super-resolution measurements.

Today SMi have harnessed these technologies to overcome major challenges in a number of clinical and scientific areas:

Single molecule imaging can be widely used for a broad range of experimental approaches. Enabling scientists to directly observe individual molecules provides irrefutable evidence of that molecule’s existence and allows highly accurate quantification. Such high-resolution measurements would be ground-breaking for biomedical research.

Membrane proteins have huge potential as drug targets, but are challenging to work with as they are often unstable when examined using traditional biochemical techniques. A technology that aids the development of novel therapeutics targeting membrane proteins would be seen as a turning point for the pharmaceutical sector.

As the COVID-19 pandemic demonstrated, diagnostic technologies have come a long way in helping to combat the spread of infectious diseases, but are still deficient in a number of areas including high false negative rates and the slow turnaround of test results. A method that is faster and more accurate could transform routine diagnosis for cancer, infectious disease, and inheritable disorders.

To learn more about SMi’s cutting edge technology please visit: https://smisystems.co.uk/

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