Case Study

Pulmonary Arterial Hypertension Animation

Pulmonary Arterial Hypertension Animation

Pulmonary arterial hypertension (PAH) occurs when pulmonary arteries thicken or become rigid, making blood flow more difficult. This causes the heart to work harder to push blood through the arteries, which are no longer able to carry adequate blood to the lungs. As a result, the body doesn’t get the oxygen it needs which causes shortness of breath, chest pain, dizziness, fainting, swelling in arms and legs (edema), chest pressure or pain (angina), and racing pulse.

There is no cure for PAH and often the life expectancy of a PAH patient is between 5-7 years after diagnosis despite a combination of lifestyle changes, medicines (vasodilators), and surgeries which may alter the progression of the disease. Within years, everyday activities such as walking and showering, will eventually become impossible and many patients will require supplementary oxygen.

Cambridge Filmworks have produced a new animation highlighting Acceleron’s preclinical trial with Sotatercept in PAH which demonstrated superior results to standard of care (vasodilators), showing the product candidate’s potential to be a disease-modifying therapy.

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Cambridge Filmworks

Cambridge Video Production

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